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DeCS
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Descriptor English:
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Aphasia, Primary Progressive
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Descriptor Spanish:
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afasia primaria progresiva
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Descriptor Portuguese:
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Afasia Primária Progressiva
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Synonyms English:
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Aphasias, Primary Progressive
Mesulam Syndrome
Mesulam's Syndrome
Primary Progressive Aphasia
Primary Progressive Aphasias
Progressive Aphasia, Primary
Progressive Aphasias, Primary
Syndrome, Mesulam
Syndrome, Mesulam's
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Tree Number:
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C10.228.140.380.132
C10.597.606.150.500.800.100.155
C23.888.592.604.150.500.800.100.155
F03.615.400.125
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Definition English:
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A progressive form of dementia characterized by the global loss of language abilities and initial preservation of other cognitive functions. Fluent and nonfluent subtypes have been described. Eventually a pattern of global cognitive dysfunction, similar to ALZHEIMER DISEASE, emerges. Pathologically, there are no Alzheimer or PICK DISEASE like changes, however, spongiform changes of cortical layers II and III are present in the TEMPORAL LOBE and FRONTAL LOBE. (From Brain 1998 Jan;121(Pt 1):115-26) |
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Indexing Annotation English:
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a clinical entity: do not confuse with descriptions of the progression of aphasia in case reports
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History Note English:
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1996
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Allowable Qualifiers English:
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Record Number:
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32833
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Unique Identifier:
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D018888
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Occurrence in VHL:
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Similar:
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DeCS
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